| 1. Round | 12/07/2015 | CS Universitatea Craiova | - | FC Botoşani | 0:0 | ||||
| 2. Round | 20/07/2015 | FC Botoşani | - | FC Viitorul Constanța | 2:2 | ||||
| 5. Round | 07/08/2015 | FC Voluntari | - | FC Botoşani | 1:1 | ||||
| 6. Round | 11/08/2015 | FC Botoşani | - | CSM Studențesc Iași | 1:0 | ||||
| 7. Round | 14/08/2015 | Petrolul Ploieşti | - | FC Botoşani | 2:1 | ||||
| 8. Round | 22/08/2015 | FC Botoşani | - | Pandurii Târgu Jiu | 0:2 | ||||
| 9. Round | 31/08/2015 | CFR Cluj | - | FC Botoşani | 3:1 | ||||
| 10. Round | 12/09/2015 | Concordia Chiajna | - | FC Botoşani | 0:0 | ||||
| 11. Round | 20/09/2015 | FC Botoşani | - | Dinamo Bucureşti | 1:1 | ||||
| 12. Round | 27/09/2015 | Astra Giurgiu | - | FC Botoşani | 1:0 | ||||
| 13. Round | 04/10/2015 | FC Botoşani | - | ASA Târgu Mureş | 1:1 | ||||
| 14. Round | 16/10/2015 | FC Botoşani | - | CS Universitatea Craiova | 3:2 | ||||
| 15. Round | 26/10/2015 | FC Viitorul Constanța | - | FC Botoşani | 3:1 | ||||
| 16. Round | 02/11/2015 | FC Botoşani | - | ACS Poli Timişoara | 1:1 | ||||
| 17. Round | 08/11/2015 | FC Steaua Bucureşti | - | FC Botoşani | 5:3 | ||||
| 18. Round | 23/11/2015 | FC Botoşani | - | FC Voluntari | 2:2 |
Bulgaria