| 2. Round | 28/08/2010 | FC St. Pauli | - | 1899 Hoffenheim | 0:1 | ||||
| 6. Round | 24/09/2010 | 1. FC Köln | - | 1899 Hoffenheim | 1:1 | ||||
| 7. Round | 02/10/2010 | 1. FSV Mainz 05 | - | 1899 Hoffenheim | 4:2 | ||||
| 10. Round | 31/10/2010 | 1899 Hoffenheim | - | Hannover 96 | 4:0 | ||||
| 14. Round | 27/11/2010 | 1899 Hoffenheim | - | Bayer Leverkusen | 2:2 | ||||
| 18. Round | 15/01/2011 | Werder Bremen | - | 1899 Hoffenheim | 2:1 |
Ghana