| 2. Round | 28/08/2021 | Club Brugge KV [U18] | - | Standard Liège [U18] | 2:1 | ||||
| 4. Round | 11/09/2021 | Royal Antwerp FC [U18] | - | Standard Liège [U18] | 1:2 |  |
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| 5. Round | 18/09/2021 | Standard Liège [U18] | - | Cercle Brugge [U18] | 5:0 | |
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| 7. Round | 02/10/2021 | Standard Liège [U18] | - | Oud-Heverlee Leuven [U18] | 3:1 | ||||
| 9. Round | 16/10/2021 | Standard Liège [U18] | - | KVC Westerlo [U18] | 2:0 | ||||
| 13. Round | 20/11/2021 | SV Zulte Waregem [U18] | - | Standard Liège [U18] | 0:0 | |
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| 15. Round | 15/01/2022 | Standard Liège [U18] | - | Club Brugge KV [U18] | 0:1 | ||||
| 16. Round | 22/01/2022 | Sporting Charleroi [U18] | - | Standard Liège [U18] | 0:2 | ||||
| 20. Round | 19/02/2022 | Oud-Heverlee Leuven [U18] | - | Standard Liège [U18] | 3:3 | ||||
| 21. Round | 05/03/2022 | Standard Liège [U18] | - | Royal Antwerp FC [U18] | 6:0 | ||||
| 22. Round | 12/03/2022 | KVC Westerlo [U18] | - | Standard Liège [U18] | 3:6 | |
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| 25. Round | 02/04/2022 | KV Mechelen [U18] | - | Standard Liège [U18] | 0:3 | ||||
| 17. Round | 09/04/2022 | Standard Liège [U18] | - | KRC Genk [U18] | 0:2 | ||||
| 26. Round | 23/04/2022 | Standard Liège [U18] | - | SV Zulte Waregem [U18] | 3:2 |
Belgium