| 1. Round | 10/08/2008 | Colón de Santa Fe | - | River Plate | 1:1 | ||||
| 3. Round | 23/08/2008 | Banfield | - | River Plate | 2:1 |  |
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| 4. Round | 31/08/2008 | River Plate | - | San Lorenzo | 0:0 | ||||
| 5. Round | 14/09/2008 | Arsenal de Sarandí | - | River Plate | 2:2 | |
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| 6. Round | 17/09/2008 | River Plate | - | Vélez Sarsfield | 1:2 | ||||
| 10. Round | 19/10/2008 | River Plate | - | Boca Juniors | 0:1 | ||||
| 11. Round | 26/10/2008 | Gimnasia de Jujuy | - | River Plate | 1:0 | ||||
| 12. Round | 29/10/2008 | River Plate | - | Newell's Old Boys | 1:1 | ||||
| 14. Round | 09/11/2008 | River Plate | - | Huracán | 3:3 | |
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| 15. Round | 16/11/2008 | Independiente | - | River Plate | 0:1 | |
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| 16. Round | 23/11/2008 | River Plate | - | Argentinos Juniors | 1:2 | |
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| 17. Round | 30/11/2008 | Tigre | - | River Plate | 3:1 | |
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| 18. Round | 06/12/2008 | River Plate | - | Godoy Cruz | 1:2 | |
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| 19. Round | 13/12/2008 | Estudiantes | - | River Plate | 1:1 |
Colombia
Venezuela 
