| 7. Round | 22/08/2022 | Pirin Blagoevgrad | - | PFC Ludogorets Razgrad | 0:4 | ||||
| 8. Round | 28/08/2022 | Hebar Pazardzhik | - | Pirin Blagoevgrad | 0:0 | ||||
| 9. Round | 02/09/2022 | Pirin Blagoevgrad | - | Botev Vratsa | 2:1 | ||||
| 10. Round | 12/09/2022 | Arda Kardzhali | - | Pirin Blagoevgrad | 0:0 | ||||
| 11. Round | 17/09/2022 | Pirin Blagoevgrad | - | Lokomotiv Sofia | 0:1 |  |
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| 12. Round | 03/10/2022 | CSKA Sofia | - | Pirin Blagoevgrad | 2:1 | |
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| 13. Round | 07/10/2022 | Pirin Blagoevgrad | - | PFC Beroe | 0:0 | ||||
| 14. Round | 15/10/2022 | Botev Plovdiv | - | Pirin Blagoevgrad | 3:1 | ||||
| 15. Round | 24/10/2022 | Pirin Blagoevgrad | - | Septemvri Sofia | 1:4 | |
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| 16. Round | 28/10/2022 | Pirin Blagoevgrad | - | Lokomotiv Plovdiv | 0:0 | ||||
| 17. Round | 05/11/2022 | CSKA 1948 Sofia | - | Pirin Blagoevgrad | 2:1 | ||||
| 18. Round | 11/11/2022 | Pirin Blagoevgrad | - | Spartak Varna | 3:1 |  |
Bulgaria