| 1. Round | 10/04/2022 | Rēzeknes FA | - | FK Tukums 2000 II | 3:2 | ||||
| 3. Round | 22/04/2022 | FS Jelgava | - | FK Tukums 2000 II | 6:1 | ||||
| 4. Round | 01/05/2022 | FK Tukums 2000 II | - | AFA Olaine | 3:3 |  |
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| 5. Round | 08/05/2022 | Grobiņas SC | - | FK Tukums 2000 II | 6:0 | ||||
| 6. Round | 15/05/2022 | FK Tukums 2000 II | - | Salaspils FC | 1:2 | ||||
| 7. Round | 21/05/2022 | Saldus SS/Leevon | - | FK Tukums 2000 II | 0:1 | ||||
| 9. Round | 19/06/2022 | FK Dinamo Rīga | - | FK Tukums 2000 II | 4:0 | ||||
| 10. Round | 01/07/2022 | FK Tukums 2000 II | - | Valmiera FC II | 2:1 | ||||
| 11. Round | 17/07/2022 | JDFS Alberts | - | FK Tukums 2000 II | 1:0 | ||||
| 12. Round | 22/07/2022 | FK Tukums 2000 II | - | Rīgas Futbola skola II | 0:5 | ||||
| 25. Round | 05/11/2022 | Rīgas Futbola skola II | - | FK Tukums 2000 II | 6:0 | ||||
| 26. Round | 13/11/2022 | FK Tukums 2000 II | - | FK Smiltene | 1:2 |
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