| 5. Round | 19/09/2021 | FC Istres [Youth] | - | Nîmes Olympique [Youth] | 5:1 | ||||
| 7. Round | 03/10/2021 | AS Monaco [Youth] | - | Nîmes Olympique [Youth] | 4:2 | ||||
| 13. Round | 28/11/2021 | Nîmes Olympique [Youth] | - | SC Toulon [Youth] | 0:2 | ||||
| 14. Round | 05/12/2021 | AS Cannes [Youth] | - | Nîmes Olympique [Youth] | 6:1 | ||||
| 15. Round | 16/01/2022 | Nîmes Olympique [Youth] | - | OGC Nice [Youth] | 1:3 | ||||
| 17. Round | 20/02/2022 | Nîmes Olympique [Youth] | - | FC Istres [Youth] | 0:2 |
France