| 13. Round | 28/11/2021 | Southampton FC U23 | - | West Bromwich Albion U23 | 3:1 |  |
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| 14. Round | 06/12/2021 | West Bromwich Albion U23 | - | Middlesbrough FC U23 | 3:2 | ||||
| 17. Round | 17/01/2022 | West Bromwich Albion U23 | - | Aston Villa U23 | 2:1 |  |
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| 18. Round | 24/01/2022 | Birmingham City U23 | - | West Bromwich Albion U23 | 3:2 | |
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| 22. Round | 14/03/2022 | West Bromwich Albion U23 | - | Wolverhampton Wanderers U23 | 0:4 | ||||
| 23. Round | 21/03/2022 | West Bromwich Albion U23 | - | Nottingham Forest U23 | 0:5 | ||||
| 16. Round | 28/03/2022 | Newcastle United U23 | - | West Bromwich Albion U23 | 4:3 | |
England