| 2. Round | 21/07/2012 | Hoverla Uzhgorod | - | Shakhtar Donetsk | 1:3 | ||||
| 4. Round | 06/08/2012 | Volyn Lutsk | - | Shakhtar Donetsk | 0:4 | ||||
| 6. Round | 19/08/2012 | Chernomorets Odessa | - | Shakhtar Donetsk | 1:5 |  |
|||
| 8. Round | 02/09/2012 | Shakhtar Donetsk | - | Dinamo Kiev | 3:1 | |
|||
| 10. Round | 28/09/2012 | Shakhtar Donetsk | - | Dnipro Dnipropetrovsk | 2:1 | ||||
| 13. Round | 27/10/2012 | Tavriya Simferopol (1958-2014) | - | Shakhtar Donetsk | 0:1 | ||||
| 14. Round | 03/11/2012 | Shakhtar Donetsk | - | Metalurg Zaporizhya | 2:0 | ||||
| 15. Round | 11/11/2012 | Metalurh Donetsk | - | Shakhtar Donetsk | 0:4 | ||||
| 16. Round | 17/11/2012 | Arsenal Kiev | - | Shakhtar Donetsk | 2:0 | ||||
| 18. Round | 30/11/2012 | FK Krivbas (old) | - | Shakhtar Donetsk | 0:2 | ||||
| 19. Round | 01/03/2013 | Shakhtar Donetsk | - | Volyn Lutsk | 4:1 | ||||
| 21. Round | 16/03/2013 | Shakhtar Donetsk | - | Chernomorets Odessa | 3:0 | ||||
| 24. Round | 13/04/2013 | Shakhtar Donetsk | - | Zorya Lugansk | 3:0 | ||||
| 25. Round | 21/04/2013 | Dnipro Dnipropetrovsk | - | Shakhtar Donetsk | 1:1 | ||||
| 26. Round | 28/04/2013 | Shakhtar Donetsk | - | Metalist Kharkiv | 1:1 | ||||
| 30. Round | 26/05/2013 | Shakhtar Donetsk | - | Metalurh Donetsk | 4:0 |
Romania