| 1. Round | 19/09/2020 | Zejtun Corinthians | - | St. Luċija FC | 2:2 | ||||
| 2. Round | 27/09/2020 | St. Luċija FC | - | Hamrun Spartans | 1:4 | ||||
| 3. Round | 01/10/2020 | Sliema Wanderers | - | St. Luċija FC | 3:1 | ||||
| 4. Round | 16/10/2020 | St. Luċija FC | - | Floriana FC | 2:1 |  |
|||
| 5. Round | 20/10/2020 | Tarxien Rainbows | - | St. Luċija FC | 0:2 | ||||
| 6. Round | 25/10/2020 | St. Luċija FC | - | Valletta FC | 1:1 | ||||
| 7. Round | 30/10/2020 | Mosta FC | - | St. Luċija FC | 1:0 |  |
|||
| 8. Round | 20/11/2020 | St. Luċija FC | - | Lija Athletics FC | 3:2 | ||||
| 9. Round | 28/11/2020 | Gżira United | - | St. Luċija FC | 2:2 | |
|
||
| 10. Round | 05/12/2020 | St. Luċija FC | - | Hibernians FC | 0:3 | ||||
| 13. Round | 20/12/2020 | St. Luċija FC | - | Gudja United | 3:2 | ||||
| 14. Round | 05/01/2021 | Balzan FC | - | St. Luċija FC | 1:1 | ||||
| 15. Round | 10/01/2021 | St. Luċija FC | - | Birkirkara FC | 0:0 | ||||
| 16. Round | 17/01/2021 | St. Luċija FC | - | Zejtun Corinthians | 1:1 |  |
|||
| 18. Round | 29/01/2021 | St. Luċija FC | - | Sliema Wanderers | 0:1 | |
|||
| 20. Round | 13/02/2021 | St. Luċija FC | - | Tarxien Rainbows | 7:0 | ||||
| 21. Round | 21/02/2021 | Valletta FC | - | St. Luċija FC | 1:0 |
Japan