| 5. Round | 22/08/2010 | The Strongest | - | Universitario de Sucre | 3:0 | ||||
| 6. Round | 29/08/2010 | Blooming | - | The Strongest | 2:1 | ||||
| 8. Round | 09/09/2010 | The Strongest | - | La Paz FC | 1:3 | ||||
| 10. Round | 19/09/2010 | The Strongest | - | Real Potosí | 4:2 | ||||
| 12. Round | 03/10/2010 | Club Aurora | - | The Strongest | 2:1 | ||||
| 14. Round | 10/10/2010 | Real Mamoré | - | The Strongest | 1:0 |  |
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| 13. Round | 14/10/2010 | The Strongest | - | Bolívar | 3:2 | ||||
| 18. Round | 31/10/2010 | Jorge Wilstermann | - | The Strongest | 3:1 | ||||
| 17. Round | 04/11/2010 | The Strongest | - | Blooming | 2:1 |  |
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| 19. Round | 07/11/2010 | La Paz FC | - | The Strongest | 0:1 | |
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| 21. Round | 21/11/2010 | Real Potosí | - | The Strongest | 2:3 | |
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| 22. Round | 28/11/2010 | The Strongest | - | Oriente Petrolero | 1:1 |
Panama