| 2. Round | 13/02/2022 | Sport Boys | - | Alianza Lima | 0:0 | ||||
| 3. Round | 20/02/2022 | Alianza Lima | - | Mannucci | 3:1 |  |
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| 4. Round | 27/02/2022 | Alianza Atlético | - | Alianza Lima | 4:2 | ||||
| 5. Round | 06/03/2022 | Alianza Lima | - | Sporting Cristal | 0:1 | ||||
| 6. Round | 12/03/2022 | FBC Melgar | - | Alianza Lima | 1:0 | ||||
| 9. Round | 10/04/2022 | Alianza Lima | - | Universidad Técnica | 1:0 | ||||
| 12. Round | 01/05/2022 | Alianza Lima | - | Carlos Stein | 5:2 |  |
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| 13. Round | 09/05/2022 | Universidad San Martín | - | Alianza Lima | 0:1 | ||||
| 15. Round | 22/05/2022 | Deportivo Municipal | - | Alianza Lima | 0:3 | ||||
| 16. Round | 31/05/2022 | Alianza Lima | - | Cienciano | 1:0 | ||||
| 8. Round | 05/06/2022 | Sport Huancayo | - | Alianza Lima | 2:0 | |
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| 17. Round | 19/06/2022 | Deportivo Binacional | - | Alianza Lima | 1:0 | ||||
| 18. Round | 27/06/2022 | Alianza Lima | - | Ayacucho FC | 2:0 | |
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| 19. Round | 03/07/2022 | AD Tarma | - | Alianza Lima | 1:1 | |
Peru