2. Round | 15/08/2021 | Plaza Amador | - | Sporting San Miguelito | 0:0 | ||||
3. Round | 21/08/2021 | Sporting San Miguelito | - | Tauro FC | 1:0 | ||||
4. Round | 29/08/2021 | Sporting San Miguelito | - | Deportivo del Este | 1:1 | ||||
6. Round | 11/09/2021 | Sporting San Miguelito | - | UD Universitario | 1:0 | ||||
7. Round | 17/09/2021 | Independiente de La Chorrera | - | Sporting San Miguelito | 3:0 | ||||
10. Round | 10/10/2021 | Sporting San Miguelito | - | San Francisco FC | 1:1 | ||||
11. Round | 16/10/2021 | Atlético Chiriquí | - | Sporting San Miguelito | 1:1 |