| 1. Round | 21/07/2018 | FK Senica | - | Spartak Trnava | 1:0 | ||||
| 3. Round | 04/08/2018 | Zlaté Moravce | - | FK Senica | 4:0 | ||||
| 4. Round | 11/08/2018 | FK Senica | - | FK Železiarne Podbrezová | 1:1 | ||||
| 5. Round | 18/08/2018 | MFK Zemplín Michalovce | - | FK Senica | 1:1 | ||||
| 6. Round | 25/08/2018 | FK Senica | - | FC Nitra | 1:1 | ||||
| 9. Round | 22/09/2018 | MŠK Žilina | - | FK Senica | 5:0 | ||||
| 16. Round | 24/11/2018 | FK Senica | - | MFK Zemplín Michalovce | 2:4 | ||||
| 17. Round | 01/12/2018 | FC Nitra | - | FK Senica | 1:0 |
Venezuela