4. Round | 20/02/2021 | Guaraní | - | Club Olimpia | 0:3 | ||||
9. Round | 21/03/2021 | Cerro Porteño | - | Guaraní | 2:1 | ||||
7. Round | 29/03/2021 | Libertad | - | Guaraní | 1:1 | ||||
10. Round | 02/04/2021 | Club Nacional | - | Guaraní | 2:0 | ||||
17. Round | 22/05/2021 | Guaireña FC | - | Guaraní | 0:0 | ||||
18. Round | 29/05/2021 | Guaraní | - | Cerro Porteño | 2:0 |