| 3. Round | 03/09/2022 | Lamia | - | Asteras Tripolis | 0:0 | ||||
| 4. Round | 12/09/2022 | PAOK Saloniki | - | Lamia | 1:0 |  |
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| 6. Round | 01/10/2022 | Lamia | - | Levadiakos | 1:0 |  |
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| 7. Round | 08/10/2022 | Ionikos Nikea | - | Lamia | 1:1 | ||||
| 11. Round | 05/11/2022 | Lamia | - | Volos NFC | 2:2 | ||||
| 12. Round | 08/11/2022 | Aris Saloniki | - | Lamia | 5:0 | ||||
| 13. Round | 13/11/2022 | Lamia | - | Panetolikos | 1:3 | ||||
| 14. Round | 21/12/2022 | AEK Athen | - | Lamia | 3:0 |
Ghana