| 14. Round | 14/04/2022 | Tala'ea El Gaish SC | - | ENPPI | 1:1 | ||||
| 15. Round | 19/04/2022 | Tala'ea El Gaish SC | - | Ceramica Cleopatra | 1:0 | ||||
| 16. Round | 27/04/2022 | Al Ahly SC | - | Tala'ea El Gaish SC | 0:0 | ||||
| 17. Round | 30/04/2022 | Tala'ea El Gaish SC | - | Ismaily | 1:0 | ||||
| 18. Round | 09/05/2022 | Tala'ea El Gaish SC | - | National Bank SC | 1:1 | ||||
| 19. Round | 17/05/2022 | Zamalek | - | Tala'ea El Gaish SC | 0:1 |  |
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| 20. Round | 21/05/2022 | Tala'ea El Gaish SC | - | Al Mokawloon | 1:0 | ||||
| 21. Round | 28/05/2022 | Ghazl Al Mehalla | - | Tala'ea El Gaish SC | 0:1 |  |
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| 22. Round | 17/06/2022 | Tala'ea El Gaish SC | - | Smouha Sporting Club | 3:3 | ||||
| 23. Round | 27/06/2022 | Future FC | - | Tala'ea El Gaish SC | 0:1 | ||||
| 24. Round | 12/07/2022 | Tala'ea El Gaish SC | - | Pyramids FC | 2:2 | ||||
| 25. Round | 17/07/2022 | El Gouna | - | Tala'ea El Gaish SC | 2:1 | ||||
| 26. Round | 23/07/2022 | Tala'ea El Gaish SC | - | Misr lel-Maqasah SC | 0:0 | ||||
| 27. Round | 28/07/2022 | Pharco FC | - | Tala'ea El Gaish SC | 0:1 | ||||
| 28. Round | 31/07/2022 | Tala'ea El Gaish SC | - | Ittihad El Iskandary | 2:1 |
Egypt