| 3. Round | 25/08/2012 | Oxford United | - | Plymouth Argyle | 2:1 |  |
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| 4. Round | 01/09/2012 | Plymouth Argyle | - | Northampton Town | 3:2 | ||||
| 5. Round | 08/09/2012 | Torquay United | - | Plymouth Argyle | 0:0 | ||||
| 6. Round | 15/09/2012 | Plymouth Argyle | - | Port Vale FC | 1:3 | |
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| 7. Round | 18/09/2012 | Plymouth Argyle | - | Bristol Rovers | 1:1 | ||||
| 8. Round | 22/09/2012 | Morecambe FC | - | Plymouth Argyle | 2:3 | ||||
| 9. Round | 29/09/2012 | Plymouth Argyle | - | Southend United | 1:1 | ||||
| 10. Round | 02/10/2012 | Wycombe Wanderers | - | Plymouth Argyle | 1:1 | ||||
| 11. Round | 06/10/2012 | Plymouth Argyle | - | AFC Wimbledon | 1:2 | |
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| 22. Round | 15/12/2012 | Exeter City | - | Plymouth Argyle | 1:1 | |
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| 23. Round | 22/12/2012 | Accrington Stanley | - | Plymouth Argyle | 1:1 | ||||
| 24. Round | 26/12/2012 | Plymouth Argyle | - | Torquay United | 1:1 | ||||
| 25. Round | 29/12/2012 | Plymouth Argyle | - | Wycombe Wanderers | 0:1 | ||||
| 26. Round | 01/01/2013 | Bristol Rovers | - | Plymouth Argyle | 2:1 | ||||
| 27. Round | 05/01/2013 | Port Vale FC | - | Plymouth Argyle | 4:0 |
England