| 1. Round | 15/02/2015 | Defensor Sporting | - | Nacional | 0:0 | ||||
| 2. Round | 22/02/2015 | Rentistas | - | Defensor Sporting | 2:6 | ||||
| 3. Round | 07/03/2015 | Defensor Sporting | - | Fénix | 1:0 | ||||
| 4. Round | 15/03/2015 | Peñarol | - | Defensor Sporting | 2:0 |  |
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| 6. Round | 29/03/2015 | Juventud de Las Piedras | - | Defensor Sporting | 5:0 | ||||
| 7. Round | 05/04/2015 | Defensor Sporting | - | Tacuarembó | 1:0 | ||||
| 8. Round | 12/04/2015 | Defensor Sporting | - | Racing | 2:1 | ||||
| 9. Round | 18/04/2015 | Sud América | - | Defensor Sporting | 0:0 | ||||
| 13. Round | 24/05/2015 | Atenas | - | Defensor Sporting | 1:2 |
Uruguay