| 1. Round | 12/03/2022 | Chindia Târgoviște | - | FC Universitatea Craiova | 0:0 | ||||
| 2. Round | 19/03/2022 | Gaz Metan Mediaş | - | FC Universitatea Craiova | 0:2 | ||||
| 3. Round | 01/04/2022 | FC Universitatea Craiova | - | CS Mioveni | 1:1 | ||||
| 4. Round | 08/04/2022 | Dinamo Bucureşti | - | FC Universitatea Craiova | 1:2 | ||||
| 5. Round | 17/04/2022 | FC Universitatea Craiova | - | Academica Clinceni | 4:0 | ||||
| 6. Round | 25/04/2022 | FC Botoşani | - | FC Universitatea Craiova | 2:1 | ||||
| 7. Round | 01/05/2022 | FC Universitatea Craiova | - | UTA Arad | 1:0 |  |
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| 8. Round | 09/05/2022 | Rapid Bucureşti | - | FC Universitatea Craiova | 2:3 | |
Romania