| Round of 16 | 20/04/2022 | América de Cali | - | Unión Magdalena | 1:2 | ||||
| Round of 16 | 12/05/2022 | Unión Magdalena | - | América de Cali | 2:1 | ||||
| Quarter-finals | 29/07/2022 | La Equidad | - | Unión Magdalena | 1:1 | ||||
| Quarter-finals | 18/08/2022 | Unión Magdalena | - | La Equidad | 5:4 pso | ||||
| Semi-finals | 25/08/2022 | Atlético Junior | - | Unión Magdalena | 0:1 |  |
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| Semi-finals | 15/09/2022 | Unión Magdalena | - | Atlético Junior | 0:1 pso |
Colombia