| 8. Round | 24/08/2021 | Academia Cantolao | - | Deportivo Municipal | 2:1 |  |
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| 9. Round | 28/08/2021 | Universitario de Deportes | - | Academia Cantolao | 2:2 | ||||
| 12. Round | 23/09/2021 | Academia Cantolao | - | Deportivo Binacional | 1:2 | ||||
| 13. Round | 27/09/2021 | Cusco FC | - | Academia Cantolao | 3:2 | ||||
| 14. Round | 03/10/2021 | Academia Cantolao | - | FBC Melgar | 0:2 | ||||
| 15. Round | 16/10/2021 | Alianza Atlético | - | Academia Cantolao | 3:1 | ||||
| 16. Round | 22/10/2021 | Academia Cantolao | - | Universidad Técnica | 2:0 | ||||
| 17. Round | 30/10/2021 | Mannucci | - | Academia Cantolao | 1:0 |
Peru