| 4. Round | 29/01/2025 | ART Municipal Jalapa | - | H&H Export Sébaco | 0:1 | ||||
| 8. Round | 20/02/2025 | Club Deportivo Ocotal | - | H&H Export Sébaco | 0:0 | ||||
| 9. Round | 23/02/2025 | H&H Export Sébaco | - | Rancho Santana | 1:0 | ||||
| 10. Round | 02/03/2025 | H&H Export Sébaco | - | CD Walter Ferretti | 1:0 | ||||
| 15. Round | 06/04/2025 | H&H Export Sébaco | - | UNAN Managua | 3:1 |
Panama