| 5. Round | 25/08/2012 | Oud-Heverlee Leuven | - | RSC Anderlecht | 1:1 | ||||
| 11. Round | 19/10/2012 | RSC Anderlecht | - | Waasland-Beveren | 2:0 | ||||
| 12. Round | 27/10/2012 | Sporting Charleroi | - | RSC Anderlecht | 2:0 | ||||
| 13. Round | 30/10/2012 | RSC Anderlecht | - | KAA Gent | 5:0 | ||||
| 18. Round | 01/12/2012 | RSC Anderlecht | - | Cercle Brugge | 2:1 |  |
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| 19. Round | 08/12/2012 | RAEC Mons | - | RSC Anderlecht | 0:5 | ||||
| 22. Round | 27/12/2012 | RSC Anderlecht | - | Lierse SK (old) | 4:1 | |
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| 26. Round | 10/02/2013 | Waasland-Beveren | - | RSC Anderlecht | 1:2 | ||||
| 27. Round | 15/02/2013 | RSC Anderlecht | - | Sporting Charleroi | 2:0 | ||||
| 29. Round | 09/03/2013 | RSC Anderlecht | - | KV Mechelen | 1:0 | ||||
| 30. Round | 16/03/2013 | KAA Gent | - | RSC Anderlecht | 1:1 |
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