| 1. Round | 13/08/1988 | Sint-Truidense VV | - | RWD Molenbeek | 3:0 | ||||
| 2. Round | 17/08/1988 | RWD Molenbeek | - | RSC Anderlecht | 0:2 | ||||
| 3. Round | 20/08/1988 | KV Mechelen | - | RWD Molenbeek | 2:0 | ||||
| 4. Round | 24/08/1988 | RWD Molenbeek | - | Royal Antwerp FC | 0:2 | ||||
| 5. Round | 31/08/1988 | KSV Waregem | - | RWD Molenbeek | 1:0 | ||||
| 8. Round | 18/09/1988 | RWD Molenbeek | - | Cercle Brugge | 2:1 | ||||
| 9. Round | 21/09/1988 | KRC Genk | - | RWD Molenbeek | 0:0 | ||||
| 16. Round | 27/11/1988 | Sporting Lokeren | - | RWD Molenbeek | 1:1 | ||||
| 17. Round | 04/12/1988 | RWD Molenbeek | - | Club Brugge KV | 1:4 |  |
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| 18. Round | 11/12/1988 | RWD Molenbeek | - | Sint-Truidense VV | 1:2 | ||||
| 19. Round | 17/12/1988 | RSC Anderlecht | - | RWD Molenbeek | 4:1 |
Belgium