| 1. Round | 18/08/1990 | KFC Germinal Ekeren | - | Sporting Lokeren | 3:0 | ||||
| 3. Round | 28/08/1990 | Club Brugge KV | - | Sporting Lokeren | 1:0 | ||||
| 4. Round | 31/08/1990 | Sporting Lokeren | - | RSC Charleroi | 0:1 | ||||
| 5. Round | 14/09/1990 | Standard Liège | - | Sporting Lokeren | 3:1 | ||||
| 6. Round | 22/09/1990 | Sporting Lokeren | - | K. Beerschot VAV | 3:1 | ||||
| 7. Round | 29/09/1990 | KSV Waregem | - | Sporting Lokeren | 1:1 | ||||
| 9. Round | 10/10/1990 | KV Mechelen | - | Sporting Lokeren | 0:0 | ||||
| 16. Round | 01/12/1990 | KV Kortrijk | - | Sporting Lokeren | 0:1 | ||||
| 17. Round | 07/12/1990 | Sporting Lokeren | - | RSC Anderlecht | 0:1 | ||||
| 21. Round | 25/01/1991 | RSC Charleroi | - | Sporting Lokeren | 1:1 | ||||
| 25. Round | 22/02/1991 | RWD Molenbeek | - | Sporting Lokeren | 0:2 | ||||
| 26. Round | 02/03/1991 | Sporting Lokeren | - | KV Mechelen | 0:1 | ||||
| 30. Round | 19/04/1991 | Sint-Truidense VV | - | Sporting Lokeren | 0:2 | ||||
| 31. Round | 04/05/1991 | Sporting Lokeren | - | RFC Liège | 2:0 | ||||
| 32. Round | 10/05/1991 | KAA Gent | - | Sporting Lokeren | 5:1 | ||||
| 33. Round | 18/05/1991 | Sporting Lokeren | - | KV Kortrijk | 0:2 | ||||
| 34. Round | 25/05/1991 | RSC Anderlecht | - | Sporting Lokeren | 0:1 |
Belgium