| 1. Round | 21/08/2021 | Oud-Heverlee Leuven [U18] | - | KAA Gent [U18] | 0:6 | ||||
| 2. Round | 28/08/2021 | KAA Gent [U18] | - | KVC Westerlo [U18] | 3:2 | ||||
| 4. Round | 11/09/2021 | KAA Gent [U18] | - | KV Mechelen [U18] | 1:3 | ||||
| 5. Round | 18/09/2021 | RSC Anderlecht [U18] | - | KAA Gent [U18] | 5:2 | ||||
| 14. Round | 27/11/2021 | KAA Gent [U18] | - | Standard Liège [U18] | 2:3 | ||||
| 18. Round | 05/02/2022 | KAA Gent [U18] | - | RSC Anderlecht [U18] | 0:1 | ||||
| 19. Round | 12/02/2022 | KV Mechelen [U18] | - | KAA Gent [U18] | 2:3 | ||||
| 17. Round | 16/02/2022 | Club Brugge KV [U18] | - | KAA Gent [U18] | 6:2 | ||||
| 20. Round | 19/02/2022 | KAA Gent [U18] | - | Sint-Truidense VV [U18] | 0:0 | ||||
| 21. Round | 26/02/2022 | Sporting Charleroi [U18] | - | KAA Gent [U18] | 0:4 |  |
|||
| 22. Round | 12/03/2022 | KAA Gent [U18] | - | SV Zulte Waregem [U18] | 0:1 | ||||
| 23. Round | 19/03/2022 | KAA Gent [U18] | - | KRC Genk [U18] | 2:3 | ||||
| 26. Round | 23/04/2022 | Cercle Brugge [U18] | - | KAA Gent [U18] | 1:1 |
Belgium