| 1. Round | 18/07/2021 | FK Leningradets | - | FK Kairat Moskva | 2:2 | ||||
| 3. Round | 01/08/2021 | Baltika Kaliningrad 2 | - | FK Kairat Moskva | 2:1 |  |
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| 4. Round | 07/08/2021 | FK Kairat Moskva | - | Luki-Energiya Velikiye Luki | 3:0 | |
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| 5. Round | 15/08/2021 | Zenit St. Petersburg 2 | - | FK Kairat Moskva | 1:2 | ||||
| 6. Round | 21/08/2021 | FK Kairat Moskva | - | Zvezda St. Petersburg | 2:0 | ||||
| 7. Round | 29/08/2021 | Dinamo St. Petersburg | - | FK Kairat Moskva | 2:0 | |
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| 9. Round | 10/09/2021 | FK Kairat Moskva | - | FK Krasava | 3:2 | ||||
| 10. Round | 14/09/2021 | FK Chita | - | FK Kairat Moskva | 1:1 | |
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| 13. Round | 30/09/2021 | FK Kairat Moskva | - | Baltika Kaliningrad 2 | 1:3 | ||||
| 14. Round | 04/10/2021 | Luki-Energiya Velikiye Luki | - | FK Kairat Moskva | 0:0 | ||||
| 15. Round | 10/10/2021 | FK Kairat Moskva | - | Zenit St. Petersburg 2 | 3:0 |
Kazakhstan