| 1. Round | 07/01/2023 | Club Necaxa | - | Atlético San Luis | 2:3 |  |
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| 2. Round | 14/01/2023 | Atlético San Luis | - | Deportivo Guadalajara | 0:0 | ||||
| 3. Round | 21/01/2023 | CF Monterrey | - | Atlético San Luis | 3:1 | ||||
| 4. Round | 29/01/2023 | UANL Tigres | - | Atlético San Luis | 0:0 | ||||
| 8. Round | 18/02/2023 | Atlético San Luis | - | Santos Laguna | 1:1 | ||||
| 9. Round | 26/02/2023 | Deportivo Toluca | - | Atlético San Luis | 2:0 | ||||
| 12. Round | 18/03/2023 | Cruz Azul | - | Atlético San Luis | 1:0 |  |
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| 14. Round | 09/04/2023 | Pumas UNAM | - | Atlético San Luis | 3:1 | ||||
| 15. Round | 14/04/2023 | Atlético San Luis | - | FC Juárez | 2:0 | ||||
| 16. Round | 23/04/2023 | CF Pachuca | - | Atlético San Luis | 2:1 | ||||
| 17. Round | 30/04/2023 | Atlético San Luis | - | Atlas Guadalajara | 0:0 |
Spain