| 1. Round | 28/11/2020 | US Biskra | - | JSM Skikda | 1:0 |  |
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| 2. Round | 05/12/2020 | US Biskra | - | NA Hussein Dey | 0:0 | ||||
| 8. Round | 15/01/2021 | US Biskra | - | USM Bel Abbes | 0:1 | ||||
| 9. Round | 22/01/2021 | Olympique Médéa | - | US Biskra | 1:0 | ||||
| 12. Round | 06/02/2021 | US Biskra | - | CS Constantine | 0:1 | ||||
| 15. Round | 26/02/2021 | JS Saoura | - | US Biskra | 4:0 | ||||
| 23. Round | 26/05/2021 | Paradou AC | - | US Biskra | 1:1 | ||||
| 25. Round | 13/06/2021 | JS Kabylie | - | US Biskra | 1:1 | ||||
| 27. Round | 26/06/2021 | USM Bel Abbes | - | US Biskra | 1:0 | ||||
| 28. Round | 01/07/2021 | US Biskra | - | Olympique Médéa | 2:2 | ||||
| 31. Round | 13/07/2021 | CS Constantine | - | US Biskra | 1:1 | ||||
| 33. Round | 23/07/2021 | USM Alger | - | US Biskra | 2:1 | ||||
| 34. Round | 27/07/2021 | US Biskra | - | JS Saoura | 1:2 | ||||
| 35. Round | 09/08/2021 | ES Sétif | - | US Biskra | 4:0 |
Algeria