| 1. Round | 02/08/2010 | PSFC Chernomorets | - | Akademik Sofia | 0:0 | ||||
| 2. Round | 07/08/2010 | Akademik Sofia | - | Vidima Rakovski | 1:2 |  |
|||
| 3. Round | 14/08/2010 | Cherno More Varna | - | Akademik Sofia | 1:0 | ||||
| 4. Round | 21/08/2010 | Akademik Sofia | - | OFC Sliven | 0:1 | ||||
| 6. Round | 11/09/2010 | Akademik Sofia | - | Slavia Sofia | 0:4 | ||||
| 7. Round | 18/09/2010 | PFC Montana | - | Akademik Sofia | 2:2 | ||||
| 8. Round | 25/09/2010 | Akademik Sofia | - | Lokomotiv Sofia | 2:3 | ||||
| 9. Round | 03/10/2010 | PFC Kaliakra Kavarna | - | Akademik Sofia | 0:1 | |
|||
| 10. Round | 16/10/2010 | Akademik Sofia | - | Minyor Pernik | 2:0 | ||||
| 11. Round | 23/10/2010 | PFC Beroe | - | Akademik Sofia | 1:0 | ||||
| 12. Round | 30/10/2010 | Akademik Sofia | - | Pirin Blagoevgrad | 1:0 | ||||
| 13. Round | 06/11/2010 | Lokomotiv Plovdiv | - | Akademik Sofia | 3:0 | ||||
| 14. Round | 13/11/2010 | Levski Sofia | - | Akademik Sofia | 1:0 |
Bulgaria