| 11. Round | 30/09/2012 | 1899 Hoffenheim II | - | Bayern Alzenau | 1:1 | ||||
| 12. Round | 05/10/2012 | SV 07 Elversberg | - | 1899 Hoffenheim II | 2:1 | ||||
| 14. Round | 21/10/2012 | 1899 Hoffenheim II | - | SG Sonnenhof Großaspach | 2:1 |  |
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| 15. Round | 27/10/2012 | SSV Ulm 1846 | - | 1899 Hoffenheim II | 1:2 | |
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| 17. Round | 11/11/2012 | 1899 Hoffenheim II | - | Eintracht Trier | 2:3 | |
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| 18. Round | 17/11/2012 | SC Pfullendorf | - | 1899 Hoffenheim II | 0:0 | ||||
| 24. Round | 02/03/2013 | 1899 Hoffenheim II | - | Wormatia Worms | 2:0 | ||||
| 21. Round | 05/03/2013 | 1899 Hoffenheim II | - | 1. FSV Mainz 05 II | 1:0 | ||||
| 31. Round | 13/04/2013 | Bayern Alzenau | - | 1899 Hoffenheim II | 1:3 | |
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| 27. Round | 17/04/2013 | Waldhof Mannheim | - | 1899 Hoffenheim II | 1:0 | |
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| 29. Round | 30/04/2013 | Hessen Kassel | - | 1899 Hoffenheim II | 2:0 | |
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| 34. Round | 05/05/2013 | 1899 Hoffenheim II | - | SSV Ulm 1846 | 0:1 | |
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| 32. Round | 08/05/2013 | 1899 Hoffenheim II | - | 1. FC Kaiserslautern II | 2:1 | ||||
| 35. Round | 11/05/2013 | 1. FC Eschborn | - | 1899 Hoffenheim II | 1:0 | |
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| 37. Round | 18/05/2013 | 1899 Hoffenheim II | - | SC Pfullendorf | 1:2 | ||||
| 38. Round | 25/05/2013 | SC Freiburg II | - | 1899 Hoffenheim II | 4:2 |
Liechtenstein