| 9. Round | 02/03/2022 | CS Cartaginés | - | AD San Carlos | 1:1 | ||||
| 11. Round | 01/04/2022 | Sporting FC | - | AD San Carlos | 4:0 | ||||
| 13. Round | 10/04/2022 | AD San Carlos | - | Deportivo Saprissa | 4:1 | ||||
| 14. Round | 14/04/2022 | Municipal Pérez Zeledón | - | AD San Carlos | 1:0 | ||||
| 17. Round | 27/04/2022 | AD Guanacasteca | - | AD San Carlos | 2:3 | ||||
| 21. Round | 13/05/2022 | LD Alajuelense | - | AD San Carlos | 1:0 |
Costa Rica