| Group B | 15/10/2022 | Atlético Huila | - | Deportes Quindío | 2:1 | ||||
| Group B | 21/10/2022 | Deportes Quindío | - | Real Santander | 1:0 | ||||
| Group B | 23/10/2022 | Deportes Quindío | - | Tigres FC | 1:0 |  |
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| Group B | 30/10/2022 | Tigres FC | - | Deportes Quindío | 1:2 | ||||
| Group B | 03/11/2022 | Real Santander | - | Deportes Quindío | 3:2 |
Colombia