| 13. Round | 12/10/2020 | Central Español | - | Tacuarembó | 0:1 | ||||
| 14. Round | 19/10/2020 | Albion | - | Central Español | 2:1 | ||||
| 15. Round | 26/10/2020 | Central Español | - | Rocha | 3:0 | ||||
| 16. Round | 30/10/2020 | Villa Española | - | Central Español | 1:1 |  |
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| 17. Round | 02/11/2020 | Central Español | - | Atenas | 2:1 | ||||
| 18. Round | 09/11/2020 | Central Español | - | Sud América | 1:1 | ||||
| 19. Round | 16/11/2020 | Rampla Juniors | - | Central Español | 2:1 |
Uruguay