| 1. Round | 30/07/2017 | KV Oostende | - | Royal Excel Mouscron | 0:1 |  |
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| 2. Round | 05/08/2017 | Royal Excel Mouscron | - | Sporting Charleroi | 2:5 | |
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| 3. Round | 12/08/2017 | Sporting Lokeren | - | Royal Excel Mouscron | 0:2 | ||||
| 8. Round | 23/09/2017 | Royal Excel Mouscron | - | KAS Eupen | 3:2 | ||||
| 9. Round | 30/09/2017 | Royal Excel Mouscron | - | KV Mechelen | 2:2 | ||||
| 10. Round | 14/10/2017 | KRC Genk | - | Royal Excel Mouscron | 1:1 | ||||
| 11. Round | 20/10/2017 | Royal Excel Mouscron | - | Standard Liège | 1:3 | ||||
| 12. Round | 26/10/2017 | Sint-Truidense VV | - | Royal Excel Mouscron | 1:0 | ||||
| 16. Round | 24/11/2017 | KAA Gent | - | Royal Excel Mouscron | 3:1 | |
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| 18. Round | 09/12/2017 | Royal Antwerp FC | - | Royal Excel Mouscron | 1:0 |
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Italy