| 4. Round | 20/08/2021 | Unión Comercio | - | Comerciantes Unidos | 4:0 |  |
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| 5. Round | 26/08/2021 | Unión Comercio | - | Unión Huaral | 1:3 | |
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| 6. Round | 01/09/2021 | Atlético Grau | - | Unión Comercio | 2:1 | |
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| 7. Round | 07/09/2021 | Unión Comercio | - | Chavelines Juniors | 1:1 | ||||
| 8. Round | 12/09/2021 | Santos FC | - | Unión Comercio | 0:1 | ||||
| 9. Round | 16/09/2021 | Unión Comercio | - | Deportivo Coopsol | 2:1 | |
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| 10. Round | 22/09/2021 | Llacuabamba | - | Unión Comercio | 0:2 | |
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| 11. Round | 30/09/2021 | Unión Comercio | - | Juan Aurich | 3:3 | |
Argentina