| 23. Round | 05/02/2022 | RCD Mallorca | - | Cádiz CF | 2:1 | ||||
| 24. Round | 14/02/2022 | RCD Mallorca | - | Athletic Club | 3:2 | ||||
| 25. Round | 20/02/2022 | Real Betis | - | RCD Mallorca | 2:1 | ||||
| 26. Round | 26/02/2022 | RCD Mallorca | - | Valencia CF | 0:1 | ||||
| 21. Round | 02/03/2022 | RCD Mallorca | - | Real Sociedad | 0:2 | ||||
| 27. Round | 06/03/2022 | RC Celta | - | RCD Mallorca | 4:3 | ||||
| 28. Round | 14/03/2022 | RCD Mallorca | - | Real Madrid | 0:3 | ||||
| 29. Round | 20/03/2022 | Espanyol Barcelona | - | RCD Mallorca | 1:0 | ||||
| 30. Round | 02/04/2022 | Getafe CF | - | RCD Mallorca | 1:0 | ||||
| 31. Round | 09/04/2022 | RCD Mallorca | - | Atlético Madrid | 1:0 | ||||
| 32. Round | 16/04/2022 | Elche CF | - | RCD Mallorca | 3:0 | ||||
| 33. Round | 19/04/2022 | RCD Mallorca | - | CD Alavés | 2:1 | ||||
| 34. Round | 01/05/2022 | FC Barcelona | - | RCD Mallorca | 2:1 | ||||
| 35. Round | 07/05/2022 | RCD Mallorca | - | Granada CF | 2:6 |
Spain
