| 7. Round | 16/10/2021 | Sekhukhune United | - | Cape Town City FC | 1:0 | ||||
| 8. Round | 27/10/2021 | Sekhukhune United | - | AmaZulu FC | 2:0 | ||||
| 9. Round | 02/11/2021 | Orlando Pirates | - | Sekhukhune United | 2:1 |  |
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| 10. Round | 07/11/2021 | Moroka Swallows | - | Sekhukhune United | 0:1 | ||||
| 11. Round | 20/11/2021 | Sekhukhune United | - | Royal AM | 1:0 | ||||
| 12. Round | 27/11/2021 | Mamelodi Sundowns | - | Sekhukhune United | 2:0 | ||||
| 13. Round | 05/12/2021 | SuperSport United | - | Sekhukhune United | 0:1 | ||||
| 14. Round | 08/12/2021 | Sekhukhune United | - | Marumo Gallants | 0:1 | ||||
| 16. Round | 18/12/2021 | Sekhukhune United | - | SuperSport United | 0:0 | ||||
| 17. Round | 22/12/2021 | Chippa United | - | Sekhukhune United | 0:0 |  |
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| 18. Round | 15/02/2022 | Royal AM | - | Sekhukhune United | 1:0 | ||||
| 19. Round | 20/02/2022 | Sekhukhune United | - | Baroka FC | 4:0 | ||||
| 21. Round | 05/03/2022 | Cape Town City FC | - | Sekhukhune United | 2:1 | ||||
| 26. Round | 23/04/2022 | Golden Arrows | - | Sekhukhune United | 0:0 | |
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| 27. Round | 03/05/2022 | Sekhukhune United | - | Mamelodi Sundowns | 0:2 | ||||
| 30. Round | 21/05/2022 | Marumo Gallants | - | Sekhukhune United | 2:2 |
South Africa