| 1. Round | 26/10/2021 | El Gouna | - | Ceramica Cleopatra | 1:1 | ||||
| 2. Round | 31/10/2021 | Misr lel-Maqasah SC | - | El Gouna | 2:0 | ||||
| 3. Round | 04/11/2021 | El Gouna | - | Pharco FC | 1:0 | ||||
| 6. Round | 27/11/2021 | El Sharkia Lel Dokhan | - | El Gouna | 0:2 | ||||
| 10. Round | 23/02/2022 | Ismaily | - | El Gouna | 0:1 | ||||
| 11. Round | 01/03/2022 | El Gouna | - | National Bank SC | 1:2 | ||||
| 12. Round | 07/03/2022 | Zamalek | - | El Gouna | 2:1 | ||||
| 13. Round | 16/03/2022 | El Gouna | - | Al Mokawloon | 1:2 | ||||
| 16. Round | 25/04/2022 | Future FC | - | El Gouna | 3:2 | ||||
| 18. Round | 10/05/2022 | Ceramica Cleopatra | - | El Gouna | 3:2 | ||||
| 22. Round | 18/06/2022 | Al Masry Club | - | El Gouna | 1:0 | ||||
| 25. Round | 17/07/2022 | El Gouna | - | Tala'ea El Gaish SC | 2:1 | ||||
| 26. Round | 24/07/2022 | Al Ahly SC | - | El Gouna | 2:0 | ||||
| 27. Round | 28/07/2022 | El Gouna | - | Ismaily | 0:3 | ||||
| 29. Round | 05/08/2022 | El Gouna | - | Zamalek | 1:4 |  |
Ethiopia