| 4. Round | 16/10/2021 | SS Pennarossa | - | AC Juvenes/Dogana | 0:0 | ||||
| 12. Round | 11/12/2021 | AC Juvenes/Dogana | - | AC Libertas | 1:7 | ||||
| 13. Round | 18/12/2021 | SS Cosmos | - | AC Juvenes/Dogana | 1:1 | ||||
| 18. Round | 29/01/2022 | AC Juvenes/Dogana | - | SS Folgore/Falciano | 0:4 | ||||
| 19. Round | 06/02/2022 | AC Juvenes/Dogana | - | SS Pennarossa | 0:2 |  |
|||
| 24. Round | 05/03/2022 | AC Juvenes/Dogana | - | SC Faetano | 1:2 | ||||
| 27. Round | 20/03/2022 | AC Libertas | - | AC Juvenes/Dogana | 2:1 | ||||
| 17. Round | 06/04/2022 | SP Tre Penne | - | AC Juvenes/Dogana | 7:1 | ||||
| 30. Round | 20/04/2022 | AC Juvenes/Dogana | - | SP Tre Fiori | 0:3 |
San Marino