| 2. Round | 21/08/1990 | Sporting Lokeren | - | Lierse SK (old) | 2:0 | ||||
| 3. Round | 28/08/1990 | Lierse SK (old) | - | Cercle Brugge | 4:0 | ||||
| 4. Round | 31/08/1990 | Royal Antwerp FC | - | Lierse SK (old) | 2:0 |  |
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| 5. Round | 14/09/1990 | Lierse SK (old) | - | Sint-Truidense VV | 0:0 | ||||
| 6. Round | 22/09/1990 | RFC Liège | - | Lierse SK (old) | 0:0 | ||||
| 7. Round | 28/09/1990 | Lierse SK (old) | - | KAA Gent | 0:1 | ||||
| 8. Round | 07/10/1990 | KV Kortrijk | - | Lierse SK (old) | 1:2 | ||||
| 9. Round | 10/10/1990 | Lierse SK (old) | - | RSC Anderlecht | 0:4 | ||||
| 10. Round | 21/10/1990 | KFC Germinal Ekeren | - | Lierse SK (old) | 1:0 | |
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| 11. Round | 02/11/1990 | KRC Genk | - | Lierse SK (old) | 0:0 | ||||
| 12. Round | 09/11/1990 | Lierse SK (old) | - | Club Brugge KV | 1:1 | ||||
| 13. Round | 13/11/1990 | RSC Charleroi | - | Lierse SK (old) | 1:1 | ||||
| 15. Round | 23/11/1990 | K. Beerschot VAV | - | Lierse SK (old) | 3:0 |
Belgium