| 1. Round | 28/08/2021 | Maccabi Petach-Tikva | - | Ironi Kiryat Shmona | 1:1 | ||||
| 2. Round | 11/09/2021 | Ironi Kiryat Shmona | - | Hapoel Tel Aviv | 0:2 | ||||
| 3. Round | 19/09/2021 | Hapoel Haifa | - | Ironi Kiryat Shmona | 1:0 | ||||
| 4. Round | 25/09/2021 | Ironi Kiryat Shmona | - | Hapoel Nof HaGalil | 1:0 | ||||
| 5. Round | 02/10/2021 | Beitar Jerusalem | - | Ironi Kiryat Shmona | 1:1 | ||||
| 6. Round | 17/10/2021 | Ironi Kiryat Shmona | - | Hapoel Hadera | 0:1 | ||||
| 7. Round | 23/10/2021 | Bnei Sachnin FC | - | Ironi Kiryat Shmona | 0:3 | ||||
| 8. Round | 30/10/2021 | Ironi Kiryat Shmona | - | Maccabi Tel Aviv | 1:3 | ||||
| 9. Round | 07/11/2021 | Maccabi Haifa | - | Ironi Kiryat Shmona | 4:0 | ||||
| 10. Round | 27/11/2021 | Ironi Kiryat Shmona | - | Hapoel Be'er Sheva | 1:2 | ||||
| 11. Round | 01/12/2021 | Hapoel Jerusalem | - | Ironi Kiryat Shmona | 0:1 |  |
Ivory Coast