| 1. Round | 30/07/2022 | FC Zimbru | - | FC Sheriff | 1:1 | ||||
| 2. Round | 06/08/2022 | FC Sfîntul Gheorghe | - | FC Sheriff | 1:3 |  |
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| 3. Round | 14/08/2022 | FC Sheriff | - | Dinamo-Auto | 2:0 | ||||
| 4. Round | 21/08/2022 | FC Bălţi | - | FC Sheriff | 0:3 | |
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| 5. Round | 29/08/2022 | FC Sheriff | - | CS Petrocub | 1:1 | |
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| 7. Round | 11/09/2022 | FC Sheriff | - | FC Milsami | 2:0 | ||||
| 13. Round | 30/10/2022 | FC Sheriff | - | Dacia Buiucani | 2:1 | |
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| 14. Round | 09/11/2022 | FC Milsami | - | FC Sheriff | 0:2 |
France