| 1. Round | 31/07/2010 | KV Kortrijk | - | Club Brugge KV | 1:0 | ||||
| 2. Round | 07/08/2010 | Club Brugge KV | - | Sint-Truidense VV | 4:1 | ||||
| 3. Round | 15/08/2010 | Cercle Brugge | - | Club Brugge KV | 3:1 | ||||
| 4. Round | 22/08/2010 | Club Brugge KV | - | KV Mechelen | 1:2 | ||||
| 5. Round | 29/08/2010 | KVC Westerlo | - | Club Brugge KV | 1:2 | ||||
| 6. Round | 12/09/2010 | Club Brugge KV | - | KRC Genk | 2:2 | ||||
| 15. Round | 13/11/2010 | Club Brugge KV | - | Lierse SK (old) | 2:0 | ||||
| 16. Round | 21/11/2010 | Club Brugge KV | - | Cercle Brugge | 0:1 | ||||
| 17. Round | 28/11/2010 | Sint-Truidense VV | - | Club Brugge KV | 2:1 | ||||
| 18. Round | 05/12/2010 | Club Brugge KV | - | KVC Westerlo | 4:3 | ||||
| 19. Round | 10/12/2010 | KV Mechelen | - | Club Brugge KV | 0:1 | ||||
| 20. Round | 19/12/2010 | Club Brugge KV | - | RSC Anderlecht | 0:2 |
Belgium