| 7. Round | 17/02/2022 | Alianza Petrolera | - | Cortuluá | 0:0 | ||||
| 9. Round | 01/03/2022 | Deportivo Pasto | - | Alianza Petrolera | 1:1 | ||||
| 11. Round | 19/03/2022 | Alianza Petrolera | - | Águilas Doradas | 2:1 |  |
|||
| 12. Round | 23/03/2022 | La Equidad | - | Alianza Petrolera | 2:1 | ||||
| 13. Round | 27/03/2022 | Alianza Petrolera | - | Patriotas FC | 2:1 |
Colombia