| 7. Round | 11/09/2021 | Plymouth Argyle | - | Sheffield Wednesday | 3:0 |  |
|||
| 11. Round | 02/10/2021 | Sheffield Wednesday | - | Oxford United | 1:2 | ||||
| 17. Round | 13/11/2021 | Sheffield Wednesday | - | Gillingham FC | 1:1 | ||||
| 28. Round | 15/01/2022 | Sheffield Wednesday | - | Plymouth Argyle | 4:2 |  |
|||
| 29. Round | 22/01/2022 | Oxford United | - | Sheffield Wednesday | 3:2 | ||||
| 27. Round | 01/02/2022 | Sheffield Wednesday | - | Morecambe FC | 2:0 | ||||
| 31. Round | 05/02/2022 | Burton Albion | - | Sheffield Wednesday | 0:2 | |
|||
| 33. Round | 13/02/2022 | Sheffield Wednesday | - | Rotherham United | 0:2 | ||||
| 34. Round | 19/02/2022 | Doncaster Rovers | - | Sheffield Wednesday | 1:3 | ||||
| 36. Round | 26/02/2022 | Sheffield Wednesday | - | Charlton Athletic | 2:0 | ||||
| 24. Round | 01/03/2022 | Sheffield Wednesday | - | Burton Albion | 5:2 | ||||
| 38. Round | 12/03/2022 | Sheffield Wednesday | - | Cambridge United | 6:0 | ||||
| 40. Round | 26/03/2022 | Sheffield Wednesday | - | Cheltenham Town | 4:1 |
Netherlands
Senegal