| 18. Round | 16/01/2009 | RSC Anderlecht | - | Cercle Brugge | 1:2 | ||||
| 20. Round | 31/01/2009 | KV Kortrijk | - | RSC Anderlecht | 1:3 | ||||
| 21. Round | 07/02/2009 | RSC Anderlecht | - | RAEC Mons | 3:2 |  |
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| 22. Round | 15/02/2009 | Sporting Charleroi | - | RSC Anderlecht | 0:1 | ||||
| 19. Round | 18/02/2009 | KAA Gent | - | RSC Anderlecht | 1:2 | |
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| 23. Round | 22/02/2009 | RSC Anderlecht | - | Standard Liège | 4:2 | |
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| 25. Round | 07/03/2009 | RSC Anderlecht | - | SV Zulte Waregem | 2:0 | |
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| 26. Round | 13/03/2009 | KV Mechelen | - | RSC Anderlecht | 2:1 | |
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| 27. Round | 21/03/2009 | RSC Anderlecht | - | Germinal Beerschot | 2:0 | ||||
| 28. Round | 05/04/2009 | Sporting Lokeren | - | RSC Anderlecht | 0:0 | |
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| 29. Round | 12/04/2009 | RSC Anderlecht | - | Club Brugge KV | 1:0 | ||||
| 30. Round | 19/04/2009 | KVC Westerlo | - | RSC Anderlecht | 0:1 | |
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| 31. Round | 25/04/2009 | RSC Anderlecht | - | FCV Dender EH | 4:0 | |
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| 32. Round | 03/05/2009 | AFC Tubize | - | RSC Anderlecht | 1:1 | ||||
| 33. Round | 09/05/2009 | RSC Anderlecht | - | KSV Roeselare | 3:1 | ||||
| 34. Round | 16/05/2009 | KRC Genk | - | RSC Anderlecht | 0:2 |
Belgium