| 1. Round | 17/07/2022 | MFK Skalica | - | MFK Ružomberok | 0:2 | ||||
| 2. Round | 24/07/2022 | MFK Ružomberok | - | FK Železiarne Podbrezová | 2:2 | ||||
| 9. Round | 04/09/2022 | MFK Ružomberok | - | Spartak Trnava | 3:2 |  |
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| 10. Round | 09/09/2022 | MFK Ružomberok | - | MŠK Žilina | 0:2 | |
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| 12. Round | 30/09/2022 | MFK Ružomberok | - | MFK Skalica | 2:0 | ||||
| 13. Round | 07/10/2022 | FK Železiarne Podbrezová | - | MFK Ružomberok | 0:2 | ||||
| 14. Round | 15/10/2022 | MFK Ružomberok | - | Tatran Liptovský Mikuláš | 1:1 | ||||
| 15. Round | 22/10/2022 | MFK Ružomberok | - | Dukla Banská Bystrica | 1:1 | ||||
| 16. Round | 29/10/2022 | AS Trenčín | - | MFK Ružomberok | 0:0 | ||||
| 18. Round | 13/11/2022 | Slovan Bratislava | - | MFK Ružomberok | 2:0 | ||||
| 11. Round | 24/11/2022 | FC DAC 1904 | - | MFK Ružomberok | 1:0 | ||||
| 19. Round | 11/02/2023 | MFK Ružomberok | - | MFK Zemplín Michalovce | 1:0 |  |
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| 20. Round | 17/02/2023 | Spartak Trnava | - | MFK Ružomberok | 0:2 | |
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| 21. Round | 26/02/2023 | MŠK Žilina | - | MFK Ružomberok | 2:0 | ||||
| 22. Round | 04/03/2023 | MFK Ružomberok | - | FC DAC 1904 | 0:1 | |
Slovakia