| 1. Round | 24/07/2021 | Górnik Łęczna | - | KS Cracovia | 1:1 | ||||
| 2. Round | 30/07/2021 | Zagłębie Lubin | - | Górnik Łęczna | 3:1 | ||||
| 3. Round | 06/08/2021 | Górnik Łęczna | - | Warta Poznań | 0:4 | ||||
| 4. Round | 15/08/2021 | Śląsk Wrocław | - | Górnik Łęczna | 0:0 | ||||
| 5. Round | 21/08/2021 | Górnik Łęczna | - | Wisła Kraków | 1:3 | ||||
| 6. Round | 27/08/2021 | FKS Stal Mielec | - | Górnik Łęczna | 2:0 | ||||
| 11. Round | 16/10/2021 | Górnik Łęczna | - | Piast Gliwice | 1:1 |  |
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| 12. Round | 22/10/2021 | Radomiak Radom | - | Górnik Łęczna | 3:1 | ||||
| 13. Round | 31/10/2021 | Górnik Łęczna | - | Raków Częstochowa | 0:0 | ||||
| 14. Round | 06/11/2021 | Górnik Łęczna | - | Lech Poznań | 1:1 | ||||
| 15. Round | 21/11/2021 | Bruk-Bet Termalica Nieciecza | - | Górnik Łęczna | 1:1 | ||||
| 16. Round | 27/11/2021 | Górnik Łęczna | - | Górnik Zabrze | 1:2 | ||||
| 21. Round | 11/02/2022 | Górnik Łęczna | - | Śląsk Wrocław | 1:1 | ||||
| 27. Round | 02/04/2022 | Górnik Łęczna | - | Pogoń Szczecin | 0:4 | |
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| 28. Round | 09/04/2022 | Piast Gliwice | - | Górnik Łęczna | 1:0 | ||||
| 30. Round | 24/04/2022 | Raków Częstochowa | - | Górnik Łęczna | 2:1 | ||||
| 34. Round | 21/05/2022 | Górnik Łęczna | - | Jagiellonia Białystok | 0:1 |
Poland